Description

5-Bromo-3,4-Dihydro-2(1H)-Quinazolinone is a high-value brominated quinazolinone derivative, a crucial heterocyclic scaffold in modern organic synthesis. This compound matters as a versatile and potent building block for pharmaceutical research and development, enabling the creation of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various therapeutic areas, including kinase inhibitors and central nervous system (CNS) agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities with biological activity.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, or insecticides, leveraging the bioactive properties of the quinazolinone core.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex molecules used in advanced material science, dyes, or functional polymers.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic chemistry and drug discovery projects.
• Process Chemistry & Scale-Up: Used in the development and optimization of scalable synthetic routes for the production of target molecules at pilot and commercial scales.

Basic Information

Product Name	5-Bromo-3,4-Dihydro-2(1H)-Quinazolinone
CAS No.	1103395-95-4
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	5-Bromo-1,2,3,4-tetrahydroquinazolin-2-one; 5-Bromo-3,4-dihydro-2(1H)-quinazolinone; 5-Bromo-1,2,3,4-tetrahydro-2-quinazolinone; 2H-Quinazolin-2-one, 5-bromo-1,4-dihydro-; 5-Bromotetrahydroquinazolin-2(1H)-one; 5-Bromo-3,4-dihydroquinazolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-3,4-Dihydro-2(1H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.