Description

tert-Butyl 4-Oxo-6-Azaspiro[2.5]Octane-6-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic and lactam structure. This compound is critical for the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Key Intermediate in Medicinal Chemistry: Serves as a crucial building block for the synthesis of spirocyclic compounds with potential pharmacological activity.
• Pharmaceutical Research & Development: Used in the discovery and optimization of new drug candidates, especially for targeting neurological disorders.
• Protease Inhibitor Synthesis: A potential precursor in the development of inhibitors for various enzymes, including proteases and kinases.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and protein function.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke APIs (Active Pharmaceutical Ingredients) and advanced intermediates.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 4-Oxo-6-Azaspiro[2.5]Octane-6-Carboxylate
CAS No.	1101840-74-7
Molecular Formula	C12H19NO3
Molecular Weight	225.28 g/mol
Synonyms	6-Boc-4-oxo-6-azaspiro[2.5]octane; tert-Butyl 4-oxo-6-azaspiro[2.5]octane-6-carboxylate; 6-(tert-Butoxycarbonyl)-4-oxo-6-azaspiro[2.5]octane; 4-Oxo-6-azaspiro[2.5]octane-6-carboxylic acid tert-butyl ester; 6-Azaspiro[2.5]octane-6-carboxylic acid, 4-oxo-, 1,1-dimethylethyl ester; Boc-4-oxo-6-azaspiro[2.5]octane
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Oxo-6-Azaspiro[2.5]Octane-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.