Description

2-(2-Bromo-5-Nitrophenyl)-1,3- Dioxolane is a specialized brominated nitroaromatic compound featuring a 1,3-dioxolane protecting group. This unique structure makes it a valuable and versatile advanced pharmaceutical intermediate and key building block in organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex aromatic and heterocyclic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the bromo and nitro functional groups offer sites for further chemical modification.
• Organic Synthesis Building Block: The bromine atom is a versatile handle for cross-coupling reactions (e.g., Suzuki, Heck), while the nitro group can be reduced to an amine, enabling the creation of diverse chemical libraries.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and pigments due to its electron-withdrawing nitro group and aromatic core.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry and for exploring new reaction pathways.

Basic Information

Product Name	2-(2-Bromo-5-Nitrophenyl)-1,3- Dioxolane
CAS No.	1101131-28-5
Molecular Formula	C9H8BrNO4
Molecular Weight	274.07 g/mol
Synonyms	2-(2-Bromo-5-nitrophenyl)-1,3-dioxolane; 1,3-Dioxolane, 2-(2-bromo-5-nitrophenyl)-; 2-Bromo-5-nitrobenzaldehyde ethylene acetal; (2-Bromo-5-nitrophenyl)-1,3-dioxolane; Benzaldehyde, 2-bromo-5-nitro-, ethylene acetal
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromo-5-Nitrophenyl)-1,3- Dioxolane is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.