Description

3H-Imidazo[4,5-B]Pyridine,7-Iodo is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure makes it a critical intermediate for the development of novel pharmaceutical compounds and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic scaffold.
• Material Science: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Acts as a versatile probe or labeling agent in biochemical research and diagnostic assay development.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex derivatives.
• Academic & Contract Research: Essential for medicinal chemistry programs and synthetic methodology research in universities and CROs.

Basic Information

Product Name	3H-Imidazo[4,5-B]Pyridine,7-Iodo
CAS No.	1100318-98-6
Molecular Formula	C6H4IN3
Molecular Weight	245.02 g/mol
Synonyms	7-Iodo-3H-imidazo[4,5-b]pyridine; 7-Iodo-1H-imidazo[4,5-b]pyridine; 7-Iodoimidazo[4,5-b]pyridine; 1H-Imidazo[4,5-b]pyridine, 7-iodo-; 3H-Imidazo[4,5-b]pyridin-7-amine, 7-iodo-; 1100318-98-6; AI3-31039; AKOS040759967
EINECS	Contact for details

Quality Control

Our 3H-Imidazo[4,5-B]Pyridine,7-Iodo is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.