Description

8-Bromo-4-Chloro-6-Methylquinazoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile reactivity, particularly as a key intermediate for constructing complex pharmaceutical and agrochemical molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the quinazoline scaffold's bioactivity.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for metal complexes, and advanced polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	8-Bromo-4-Chloro-6-Methylquinazoline
CAS No.	1100207-81-5
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	4-Chloro-8-bromo-6-methylquinazoline; 6-Methyl-8-bromo-4-chloroquinazoline; 8-Bromo-4-chloro-6-methyl-quinazoline; Quinazoline, 8-bromo-4-chloro-6-methyl-; 1100207-81-5
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloro-6-Methylquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.