Description

8-Cyclopropylamino-5-Nitroquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline scaffold functionalized with a cyclopropylamino and a nitro group. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases and oncology. It is essential for research and development laboratories, contract manufacturing organizations (CMOs), and pharmaceutical companies engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex bioactive molecules and active pharmaceutical ingredients (APIs).
• Antimicrobial Agent Research: Serves as a core scaffold for developing new compounds with potential antibacterial or antifungal properties.
• Kinase Inhibitor Development: Used in the research and synthesis of targeted cancer therapies, such as kinase inhibitors.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target validation.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing complex heterocyclic systems.
• Material Science Research: Investigated for potential applications in creating functional organic materials due to its electron-accepting nitro group.

Basic Information

Product Name	8-Cyclopropylamino-5-Nitroquinoline
CAS No.	1099929-70-0
Molecular Formula	C₁₂H₁₁N₃O₂
Molecular Weight	229.24 g/mol
Synonyms	5-Nitro-8-(cyclopropylamino)quinoline; 8-(Cyclopropylamino)-5-nitroquinoline; Quinoline, 8-(cyclopropylamino)-5-nitro-; 8-Cyclopropylamino-5-nitro-quinoline; CPANQ
EINECS	Contact for details

Quality Control

Our 8-Cyclopropylamino-5-Nitroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.