Description

4-Chloro-8-Fluoro-2-Phenylquinoline is a high-value, multi-functional heterocyclic building block. This compound matters for its role as a critical synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinoline scaffold is active.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs) and other electronic materials due to its conjugated quinoline system.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in coordination chemistry.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	4-Chloro-8-Fluoro-2-Phenylquinoline
CAS No.	1099705-42-6
Molecular Formula	C15H9ClFN
Molecular Weight	257.69 g/mol
Synonyms	4-Chloro-8-fluoro-2-phenylquinoline; 2-Phenyl-4-chloro-8-fluoroquinoline; 8-Fluoro-4-chloro-2-phenylquinoline; Quinoline, 4-chloro-8-fluoro-2-phenyl-; 1099705-42-6; 4-Chloro-8-fluoro-2-phenyl-quinoline; 4-Chloro-8-fluoro-2-phenyl-chinolin
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-Fluoro-2-Phenylquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee the material meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.