Description

tert-Butyl 4-(Quinazolin-4-Ylamino)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly kinase inhibitors targeting various cancers and inflammatory diseases. It is essential for research and development laboratories, process chemistry teams, and manufacturers in the pharmaceutical and biotechnology sectors seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology research.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a crucial scaffold in the scale-up and manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a tool compound to study specific biological pathways and enzyme functions.
• Custom Synthesis: A starting material for the preparation of specialized libraries of compounds for high-throughput screening.

Basic Information

Product Name	tert-Butyl 4-(Quinazolin-4-Ylamino)Piperidine-1-Carboxylate
CAS No.	1099027-20-9
Molecular Formula	C18H24N4O2
Molecular Weight	328.41 g/mol
Synonyms	1-Boc-4-(quinazolin-4-ylamino)piperidine; 4-(Quinazolin-4-ylamino)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-((quinazolin-4-yl)amino)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(quinazolin-4-ylamino)piperidine; BOC-4-(QA)Piperidine; 1099027-20-9; 4-(Piperidin-4-ylamino)quinazoline-1-Boc protected
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Quinazolin-4-Ylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.