Description

4-Fluoro-1-Benzothiophene-2-Carbohydrazide is a high-purity, specialized organic intermediate of significant interest in advanced chemical synthesis. Its core value lies in its reactive carbohydrazide functional group, which serves as a versatile building block for constructing complex heterocyclic systems. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Synthesis Reagent: Employed in organic laboratories for the preparation of hydrazones, azoles, and other nitrogen-containing heterocycles via condensation reactions.
• Ligand Synthesis: Useful for creating chelating ligands in coordination chemistry and catalysis research.

Basic Information

Product Name	4-Fluoro-1-Benzothiophene-2-Carbohydrazide
CAS No.	1098351-44-0
Molecular Formula	C9H7FN2OS
Molecular Weight	210.23 g/mol
Synonyms	4-Fluorobenzo[b]thiophene-2-carbohydrazide; 1-Benzothiophene-2-carbohydrazide, 4-fluoro-; 4-Fluoro-1-benzothiophene-2-carboxylic acid hydrazide; 4-Fluorobenzo[b]thiophene-2-carboxylic hydrazide; 1098351-44-0; 4-F-BTH-Carbohydrazide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1-Benzothiophene-2-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability, as the compound is easily oxidized. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.