Description

2-[3,4-Dihydro-1(2H)-Quinolinyl]-5-Methylaniline is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Organic Synthesis Building Block: Used in research and development for constructing novel heterocyclic compounds and complex molecular architectures.
• Agrochemical Research: Serves as a starting material for developing new active ingredients with potential pesticidal or herbicidal activity.
• Material Science: Investigated for use in the development of organic electronic materials and specialty polymers.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and methodological studies.

Basic Information

Product Name	2-[3,4-Dihydro-1(2H)-Quinolinyl]-5-Methylaniline
CAS No.	1097785-83-5
Molecular Formula	C16H18N2
Molecular Weight	238.33 g/mol
Synonyms	5-Methyl-2-(1,2,3,4-tetrahydroquinolin-1-yl)aniline; 2-(3,4-Dihydro-2H-quinolin-1-yl)-5-methylaniline; 1-(4-Amino-2-methylphenyl)-1,2,3,4-tetrahydroquinoline; 5-Methyl-2-(3,4-dihydro-1(2H)-quinolinyl)benzenamine; 2-(1,2,3,4-Tetrahydroquinolin-1-yl)-5-methylphenylamine
EINECS	Contact for details

Quality Control

Our 2-[3,4-Dihydro-1(2H)-Quinolinyl]-5-Methylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support custom synthesis and can tailor purity specifications to meet specific R&D or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening sealed containers. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.