Description

6-(2,6-Difluorobenzoyl)-1,2,3,4-Tetrahydroquinolin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluorobenzoyl-substituted tetrahydroquinolinone scaffold. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high selectivity and potency. It is primarily sought after by research institutions and manufacturers in the global pharmaceutical and agrochemical industries for developing next-generation small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the fluorinated quinolinone structure.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in academic and industrial R&D.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and functional materials requiring fluorinated aromatic systems.
• Contract Manufacturing & Development (CDMO): Supplied to CDMOs for custom synthesis projects and scale-up production for clinical trial materials.

Basic Information

Product Name	6-(2,6-Difluorobenzoyl)-1,2,3,4-Tetrahydroquinolin-2-One
CAS No.	1097107-50-0
Molecular Formula	C16H11F2NO2
Molecular Weight	287.26 g/mol
Synonyms	6-(2,6-Difluorobenzoyl)-3,4-dihydro-2(1H)-quinolinone; 2,6-Difluoro-α-oxo-1,2,3,4-tetrahydro-2-quinolineacetophenone; 1,2,3,4-Tetrahydro-6-(2,6-difluorobenzoyl)-2-quinolinone; 6-(2,6-Difluorobenzoyl)-1,2,3,4-tetrahydroquinolin-2-one; 1097107-50-0; 6-(2,6-Difluorobenzoyl)-3,4-dihydroquinolin-2(1H)-one; 2(1H)-Quinolinone, 6-(2,6-difluorobenzoyl)-1,2,3,4-tetrahydro-
EINECS	Contact for details

Quality Control

Our 6-(2,6-Difluorobenzoyl)-1,2,3,4-Tetrahydroquinolin-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.