Description

2-[2-(2H-1,3-Benzodioxol-5-Yl)-1,3-Thiazol-4-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining benzodioxole and thiazole moieties. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for the development of new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic framework for bioactivity.
• Biochemical Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API batches.
• Academic Research: Utilized in university and institutional laboratories for organic synthesis methodology development and chemical biology studies.

Basic Information

Item	Detail
Product Name	2-[2-(2H-1,3-Benzodioxol-5-Yl)-1,3-Thiazol-4-Yl]Acetic Acid
CAS No.	1097005-91-8
Molecular Formula	C₁₂H₉NO₄S
Molecular Weight	263.27 g/mol
Synonyms	2-[2-(1,3-Benzodioxol-5-yl)-1,3-thiazol-4-yl]acetic acid; 2-(2-(Benzo[d][1,3]dioxol-5-yl)thiazol-4-yl)acetic acid; 4-Thiazoleacetic acid, 2-(1,3-benzodioxol-5-yl)-; (2-(Benzo[d][1,3]dioxol-5-yl)thiazol-4-yl)acetic acid; 1097005-91-8; 2-(2-(2H-1,3-Benzodioxol-5-yl)-1,3-thiazol-4-yl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of 2-[2-(2H-1,3-Benzodioxol-5-Yl)-1,3-Thiazol-4-Yl]Acetic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications tailored to meet project-specific requirements. Certificates of Analysis (COA) documenting purity (typically by HPLC), identity (by IR, NMR), and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.