Description

4-(3-Methoxyphenyl)-1H-Pyrrole-3-Carboxylic Acid is a high-purity, functionalized pyrrole derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a methoxyphenyl substituent, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific pyrrole-based architectures for bioactivity.
• Material Science Research: Serves as a precursor for organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs) due to its electron-rich pyrrole core and functional handles.
• Chemical Biology & Proteomics: Employed in the synthesis of specialized probes, linkers, and tags for studying biological systems and protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including cross-coupling reactions and multicomponent syntheses.
• Fine Chemical Production: Incorporated into the manufacture of dyes, pigments, and other performance chemicals where the methoxyphenyl-pyrrole unit imparts specific optical or chemical properties.

Basic Information

Product Name	4-(3-Methoxyphenyl)-1H-Pyrrole-3-Carboxylic Acid
CAS No.	1096790-29-2
Molecular Formula	C12H11NO3
Molecular Weight	217.22 g/mol
Synonyms	4-(3-Methoxyphenyl)-1H-pyrrole-3-carboxylic acid; 1H-Pyrrole-3-carboxylic acid, 4-(3-methoxyphenyl)-; 4-(3-Methoxyphenyl)pyrrole-3-carboxylic acid; 3-Carboxy-4-(3-methoxyphenyl)pyrrole; 4-(m-Methoxyphenyl)-1H-pyrrole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Methoxyphenyl)-1H-Pyrrole-3-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations for industrial chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.