Description

8-Nitroguanosine 2',3',5'-Triacetate is a key protected nucleoside derivative used as a critical building block in organic synthesis and pharmaceutical research. This compound is essential for researchers and manufacturers developing novel nucleoside analogs, which are a cornerstone of antiviral and anticancer therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical synthesis facilities, and academic institutions focused on medicinal chemistry and nucleic acid chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of modified guanosine analogs and nucleoside-based active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Serves as a building block for the development of novel antiviral compounds targeting viral polymerases.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore new therapeutic agents in oncology and virology.
• Bioconjugation & Probe Development: Facilitates the creation of labeled nucleosides for biochemical assays and diagnostic probe development.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring protected, functionalized nucleoside scaffolds.
• Academic & Institutional Research: A valuable reagent for universities and research institutes studying nucleic acid chemistry and drug discovery pathways.

Basic Information

Product Name	8-Nitroguanosine 2',3',5'-Triacetate
CAS No.	1096020-95-9
Molecular Formula	C16H18N6O10
Molecular Weight	454.35 g/mol
Synonyms	8-Nitro-2',3',5'-tri-O-acetylguanosine; Guanosine, 8-nitro-, 2',3',5'-triacetate; 8-Nitroguanosine triacetate; 2',3',5'-Tri-O-acetyl-8-nitroguanosine; 8-Nitro-2',3',5'-tri-O-acetyl-guanosine; 8-Nitro-2',3',5'-triacetyl-guanosine; 8-Nitro-TAG
EINECS	Contact for details

Quality Control

Our 8-Nitroguanosine 2',3',5'-Triacetate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.