Description

Dimethyl 4-Bromo-2-Nitrobenzylphosphonate is a high-purity organophosphorus compound primarily used as a key synthetic intermediate in advanced organic chemistry. This compound matters for its role in facilitating complex molecular transformations, particularly in the construction of pharmacologically active scaffolds. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing benzylphosphonate or nitroaromatic motifs.
• Agrochemical Research: Used in the development of new herbicides, pesticides, and plant growth regulators that leverage its reactive bromo and nitro functional groups.
• Ligand and Catalyst Synthesis: Serves as a precursor for phosphonate-based ligands used in transition metal catalysis and organocatalysis.
• Material Science: Employed in the research and development of advanced materials, such as flame retardants or functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme activity and biological pathways.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for creating complex biaryl structures.

Basic Information

Product Name	Dimethyl 4-Bromo-2-Nitrobenzylphosphonate
CAS No.	1094851-36-1
Molecular Formula	C9H11BrNO5P
Molecular Weight	324.07 g/mol
Synonyms	Dimethyl (4-Bromo-2-nitrobenzyl)phosphonate; Phosphonic acid, P-[(4-bromo-2-nitrophenyl)methyl]-, dimethyl ester; (4-Bromo-2-nitrobenzyl)phosphonic acid dimethyl ester; Dimethyl (4-bromo-2-nitrobenzyl)phosphonate; 4-Bromo-2-nitrobenzylphosphonic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our Dimethyl 4-Bromo-2-Nitrobenzylphosphonate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.