Description

3-Amino-1-[4-(Difluoromethoxy)Phenyl]Urea is a specialized organic compound featuring a urea core substituted with an amino group and a difluoromethoxy phenyl moiety. This unique molecular structure makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex molecules with specific biological activities. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used as a precursor in the synthesis of novel herbicides, fungicides, or insecticides that leverage the difluoromethoxy group for enhanced activity.
• Chemical Research: Serves as a versatile reagent in academic and industrial laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Material Science: Potential intermediate for the synthesis of specialty polymers or advanced materials requiring fluorine-containing aromatic units.
• Bioconjugation & Probe Development: The amino group allows for functionalization, making it useful in creating labeled compounds or probes for biochemical studies.

Basic Information

Product Name	3-Amino-1-[4-(Difluoromethoxy)Phenyl]Urea
CAS No.	1094769-82-0
Molecular Formula	C8H9F2N3O2
Molecular Weight	217.17 g/mol
Synonyms	1-(4-(Difluoromethoxy)phenyl)-3-aminourea; Urea, N-(4-(difluoromethoxy)phenyl)-N'-amino-; 3-Amino-1-(4-(difluoromethoxy)phenyl)urea; N-(4-(Difluoromethoxyphenyl))-N'-aminourea; 4-(Difluoromethoxy)phenylaminourea; (4-(Difluoromethoxy)phenyl)urea-3-amine; DFMPU (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Amino-1-[4-(Difluoromethoxy)Phenyl]Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), impurity profiles, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.