Description

1-Ethyl-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of complex molecular architectures. Pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical producers need this material for its role in constructing pyrazolopyridine-based compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a precursor for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed as a molecular scaffold or probe in biochemical research to study protein-ligand interactions.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical reactions involving fused heterocycles.

Basic Information

Product Name	1-Ethyl-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid
CAS No.	1094442-46-2
Molecular Formula	C11H11N3O2
Molecular Weight	217.23 g/mol
Synonyms	1-Ethyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid; 5-Carboxy-1-ethyl-6-methyl-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 1-ethyl-6-methyl-; 1-Ethyl-6-methylpyrazolo[3,4-b]pyridine-5-carboxylic acid; 1094442-46-2; 1-Ethyl-6-methyl-1H-1,5,6,7-tetraaza-indene-5-carboxylic acid (alternative fused ring naming).
EINECS	Contact for details

Quality Control

Our 1-Ethyl-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical and agrochemical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is compatible with strong acids and organic solvents but should be kept away from incompatible materials. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.