Description

n-Propyl 4-Bromo-2-Fluorobenzylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzylamine structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo and fluoro substituents into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the halogenated aromatic ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production.
• Academic and Industrial R&D: Used in research laboratories for method development and exploring new chemical entities.

Basic Information

Product Name	n-Propyl 4-Bromo-2-Fluorobenzylamine
CAS No.	1094257-47-2
Molecular Formula	C10H13BrFN
Molecular Weight	246.12 g/mol
Synonyms	1-(4-Bromo-2-fluorophenyl)-N-propylmethanamine; 4-Bromo-2-fluoro-N-propylbenzylamine; (4-Bromo-2-fluorobenzyl)(propyl)amine; 1-(4-Bromo-2-fluorobenzyl)propylamine; Benzenemethanamine, 4-bromo-2-fluoro-N-propyl-; N-Propyl-1-(4-bromo-2-fluorophenyl)methanamine
EINECS	Contact for details

Quality Control

Our n-Propyl 4-Bromo-2-Fluorobenzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.