Description

Chloro[[1,3-Bis(2,6-Diisopropylphenyl)Imidazol-2-Ylidene](N,n-Dimethyl-3,5-Dimethoxybenzylamine)Palladium(II)] is a highly specialized, air-stable N-heterocyclic carbene (NHC) palladium complex designed for demanding cross-coupling catalysis. This compound matters because it offers superior catalytic activity and stability compared to traditional phosphine-based catalysts, enabling more efficient and robust synthetic transformations. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance catalysts for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi cross-coupling reactions in API development.
• Agrochemical Manufacturing: Enables the efficient synthesis of complex, bioactive molecules for crop protection agents.
• Advanced Material Research: Used in the polymerization and functionalization of organic electronic materials and polymers.
• Methodology Development: A preferred catalyst in academic and industrial labs for developing new C-C and C-N bond-forming reactions.
• Scale-up Process Chemistry: Its stability makes it suitable for transitioning reactions from milligram to kilogram scale in pilot plants.
• Fine Chemical Production: Catalyzes the synthesis of specialty flavors, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	Chloro[[1,3-Bis(2,6-Diisopropylphenyl)Imidazol-2-Ylidene](N,n-Dimethyl-3,5-Dimethoxybenzylamine)Palladium(II)]
CAS No.	1093348-08-3
Molecular Formula	C39H53ClN3O2Pd
Molecular Weight	746.70 g/mol
Synonyms	Palladium, chloro[1,3-bis(2,6-diisopropylphenyl)-2-imidazolidinylidene][2-[(dimethylamino)methyl]-3,5-dimethoxyphenyl-kC]-; (SIPr)Pd(Cl)(3,5-(MeO)2BnNMe2); NHC-Pd Complex; Pd-SIPr Amine Complex; Chloro(1,3-bis(2,6-diisopropylphenyl)imidazolin-2-ylidene)(3,5-dimethoxy-N,N-dimethylbenzylamine)palladium(II); [Pd(Cl)(SIPr)(3,5-(MeO)2BnNMe2)]; Palladium NHC-Amine Catalyst; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of our Chloro[[1,3-Bis(2,6-Diisopropylphenyl)Imidazol-2-Ylidene](N,n-Dimethyl-3,5-Dimethoxybenzylamine)Palladium(II)] is synthesized and handled under strict inert atmosphere conditions to prevent decomposition. We employ advanced analytical techniques including NMR, HPLC, and elemental analysis to verify identity, purity, and catalytic competency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet the documentation requirements of cGMP, ICH Q7, and ISO 9001 quality systems.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the sealed container under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is hygroscopic (moisture-sensitive) and easily oxidized; exposure to air and moisture must be minimized. The storage area should be cool, dry, and well-ventilated.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (NMR)	Conforms to structure
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Palladium (Pd) Content	13.5 - 15.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.