Description

Benzene, 1-(1,1-Dimethylethoxy)-4-Ethynyl- is a specialized aromatic compound featuring both a tert-butoxy protecting group and a terminal alkyne functionality, making it a versatile and valuable intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for constructing complex chemical architectures. It is primarily utilized in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as cross-coupling reactions and the synthesis of novel polymers and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring alkyne-aryl linkages.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, resins, and advanced organic frameworks.
• Chemical Research: A valuable reagent in academic and industrial R&D for Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Employed in the synthesis of complex ligands and organometallic catalysts for asymmetric synthesis.
• Fine Chemical Production: Used in the multi-step synthesis of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Benzene, 1-(1,1-Dimethylethoxy)-4-Ethynyl-
CAS No.	1093192-41-6
Molecular Formula	C12H14O
Molecular Weight	174.24 g/mol
Synonyms	4-Ethynyl-1-(tert-butoxy)benzene; 1-tert-Butoxy-4-ethynylbenzene; p-(tert-Butoxy)phenylacetylene; 4-(tert-Butoxy)phenylacetylene; 1-(tert-Butoxy)-4-ethynylbenzene; 4-Ethynylphenyl tert-butyl ether; tert-Butyl 4-ethynylphenyl ether
EINECS	Contact for details

Quality Control

Our Benzene, 1-(1,1-Dimethylethoxy)-4-Ethynyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.