Description

3-(2-(Trifluoromethyl)Pyridin-4-Yl)-1H-Indazol-5-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other biologically active molecules targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its indazole-pyridine core.
• Bioconjugation & Probe Development: The amine functional group allows for derivatization and conjugation, useful in creating chemical probes for biological assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	3-(2-(Trifluoromethyl)Pyridin-4-Yl)-1H-Indazol-5-Amine
CAS No.	1093064-91-5
Molecular Formula	C14H10F3N5
Molecular Weight	305.26 g/mol
Synonyms	5-Amino-3-[2-(trifluoromethyl)-4-pyridinyl]-1H-indazole; 3-(2-(Trifluoromethyl)-4-pyridinyl)-1H-indazol-5-amine; 1H-Indazol-5-amine, 3-[2-(trifluoromethyl)-4-pyridinyl]-; 1093064-91-5; AKOS025147193; ZINC000103486764; CTK8G8731; FT-0772689
EINECS	Contact for details

Quality Control

Every batch of 3-(2-(Trifluoromethyl)Pyridin-4-Yl)-1H-Indazol-5-Amine is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.