Description

1-(4-Fluoro-Phenyl)-Propylamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a versatile synthon for constructing more complex molecules, particularly in medicinal chemistry and advanced material science. This compound is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides, leveraging the fluorine moiety for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials where the fluoro-phenyl group imparts specific electronic or physical properties.
• Chemical Biology & Proteomics: Utilized as a reactive handle or spacer in the design of molecular probes, affinity tags, and bioconjugation reagents for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns for client-specific molecules.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-Propylamine Hydrochloride
CAS No.	1092797-76-6
Molecular Formula	C9H13ClFN
Molecular Weight	189.66 g/mol
Synonyms	1-(4-Fluorophenyl)propan-1-amine hydrochloride; 4-Fluoro-α-ethylbenzylamine hydrochloride; 1-(4-Fluorophenyl)-1-propylamine HCl; (4-Fluorophenyl)propylamine hydrochloride; 1-Amino-1-(4-fluorophenyl)propane hydrochloride; Benzenemethanamine, 4-fluoro-α-ethyl-, hydrochloride; α-Ethyl-4-fluorobenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Phenyl)-Propylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.