Description

3-Cyclohexyl-4-Fluoro-1H-Indole is a high-value, fluorinated indole derivative with a unique cyclohexyl substituent, serving as a critical advanced intermediate in modern synthetic chemistry. Its molecular architecture makes it a versatile building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and indole core can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials and specialty polymers, leveraging its conjugated system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: A valuable reagent for method development and discovery chemistry in university and CRO laboratories.
• Fluorine Chemistry Libraries: A core structure for generating focused compound libraries to explore structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	3-Cyclohexyl-4-Fluoro-1H-Indole
CAS No.	1092574-91-8
Molecular Formula	C14H16FN
Molecular Weight	217.28 g/mol
Synonyms	4-Fluoro-3-cyclohexyl-1H-indole; 3-Cyclohexyl-4-fluoroindole; 1H-Indole, 3-cyclohexyl-4-fluoro-; 4-Fluoro-3-cyclohexylindole; 1092574-91-8
EINECS	Contact for details

Quality Control

Our 3-Cyclohexyl-4-Fluoro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.