Description

5-Chloro-2-(Trifluoromethoxy)Benzamide is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique trifluoromethoxy and benzamide structure makes it a critical precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the stability of the trifluoromethoxy group.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic compounds and functionalized aromatic systems in medicinal chemistry.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique thermal and chemical resistance properties.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for catalytic processes and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Chloro-2-(Trifluoromethoxy)Benzamide
CAS No.	1092461-18-1
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	5-Chloro-2-(trifluoromethoxy)benzamide; Benzamide, 5-chloro-2-(trifluoromethoxy)-; 2-Trifluoromethoxy-5-chlorobenzamide; 5-Chloro-α,α,α-trifluoro-o-anisamide; 1092461-18-1; 5-Chloro-2-(trifluoromethoxy)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethoxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.