Description

3-Bromo-5-(Trifluoromethoxy)Cinnamic Acid is a high-purity, multi-functional organic building block essential for advanced chemical synthesis. This compound matters because it provides a unique trifluoromethoxy-substituted cinnamate scaffold, offering enhanced lipophilicity and metabolic stability for target molecules. Pharmaceutical, agrochemical, and advanced material researchers need it for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the bioactivity of the cinnamic acid and halogenated motifs.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating fluorinated organic semiconductors and liquid crystal compounds due to its rigid, polarizable structure.
• Chemical Biology Probe Development: Employed in the design of activity-based probes and molecular tags for studying enzyme function and protein interactions.
• Polymer Modification: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with specific optical or surface properties.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and catalysis research within university and CRO laboratories.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethoxy)Cinnamic Acid
CAS No.	1092460-68-8
Molecular Formula	C₁₀H₆BrF₃O₃
Molecular Weight	311.06 g/mol
Synonyms	(E)-3-(3-Bromo-5-(trifluoromethoxy)phenyl)acrylic acid; 3-Bromo-5-(trifluoromethoxy)cinnamic acid; (2E)-3-[3-Bromo-5-(trifluoromethoxy)phenyl]prop-2-enoic acid; 3-Bromo-5-trifluoromethoxycinnamic acid; 2-Propenoic acid, 3-[3-bromo-5-(trifluoromethoxy)phenyl]-, (2E)-; 1092460-68-8; Cinnamic acid, 3-bromo-5-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Trifluoromethoxy)Cinnamic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.