Description

n-Isobutyl-4-Oxo-3,4-Dihydroquinazoline-7-Carboxamide is a high-purity, synthetically derived quinazoline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate and a valuable building block for medicinal chemists. It is primarily utilized by R&D teams in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel drug candidates, particularly in areas targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a core scaffold or building block for designing and optimizing new chemical entities in drug discovery programs.
• Kinase Inhibitor Development: Employed in the research of compounds targeting specific kinase enzymes, relevant in oncology and inflammatory diseases.
• Biochemical Tool Compound: Serves as a reference standard or probe in biochemical and pharmacological assays to study biological pathways.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value compounds.

Basic Information

Product Name	n-Isobutyl-4-Oxo-3,4-Dihydroquinazoline-7-Carboxamide
CAS No.	1092460-55-3
Molecular Formula	C₁₃H₁₅N₃O₂
Molecular Weight	245.28 g/mol
Synonyms	7-Carbamoyl-4-hydroxy-2-isobutylquinazoline; 4-Hydroxy-2-isobutylquinazoline-7-carboxamide; 2-(2-Methylpropyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide; Isobutyl-4-oxo-3,4-dihydroquinazoline-7-carboxamide; Quinazoline-7-carboxamide, 3,4-dihydro-2-(2-methylpropyl)-4-oxo-; 1092460-55-3; AI3-63598
EINECS	Contact for details

Quality Control

Every batch of n-Isobutyl-4-Oxo-3,4-Dihydroquinazoline-7-Carboxamide is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specified parameters. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.