Description

7-(Morpholine-4-Carbonyl)Quinazolin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate with a defined quinazolinone core structure. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of novel kinase inhibitors due to the quinazolinone pharmacophore.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying specific biological targets and mechanisms.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and bioorganic chemistry projects.

Basic Information

Product Name	7-(Morpholine-4-Carbonyl)Quinazolin-4(3H)-One
CAS No.	1092460-45-1
Molecular Formula	C₁₃H₁₃N₃O₃
Molecular Weight	259.26 g/mol
Synonyms	4(3H)-Quinazolinone, 7-(4-morpholinylcarbonyl)-; 7-(Morpholine-4-carbonyl)quinazolin-4(3H)-one; 7-(Morpholin-4-ylcarbonyl)quinazolin-4(3H)-one; 7-(4-Morpholinylcarbonyl)-4(3H)-quinazolinone; Quinazolin-4(3H)-one, 7-(4-morpholinylcarbonyl)-; 1092460-45-1; 7-Morpholin-4-ylcarbonylquinazolin-4-one
EINECS	Contact for details

Quality Control

Our 7-(Morpholine-4-Carbonyl)Quinazolin-4(3H)-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.