Description

4-Chloro-n-Isobutylquinazoline-7-Carboxamide is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel oncology and anti-inflammatory treatments. Our supply ensures consistent quality and reliable availability for global R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small-molecule kinase inhibitors for targeted cancer therapies.
• Biochemical Research: Used as a reference standard or building block in medicinal chemistry and drug discovery programs.
• API Development: Serves as a core structural component in the development of new Active Pharmaceutical Ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of quinazoline derivatives.

Basic Information

Product Name	4-Chloro-n-Isobutylquinazoline-7-Carboxamide
CAS No.	1092460-43-9
Molecular Formula	C₁₃H₁₄ClN₃O
Molecular Weight	263.72 g/mol
Synonyms	4-Chloro-N-isobutylquinazoline-7-carboxamide; 7-Carboxamide-4-chloro-N-isobutylquinazoline; 4-Chloro-7-(isobutylcarbamoyl)quinazoline; 1092460-43-9; Quinazoline-7-carboxamide, 4-chloro-N-(2-methylpropyl)-; 4-Chloro-N-(2-methylpropyl)quinazoline-7-carboxamide
EINECS	Contact for details

Quality Control

Our 4-Chloro-n-Isobutylquinazoline-7-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.