Description

Dansyl Ethylenediamine Hydrochloride is a high-purity, fluorescent derivatization reagent used for the sensitive detection and quantification of amines, amino acids, and other carbonyl-containing compounds. Its core value lies in enhancing analytical sensitivity and selectivity in chromatographic and spectroscopic methods, providing researchers and quality control laboratories with reliable data. This compound is essential for professionals in pharmaceutical R&D, analytical chemistry, and biotechnology who require precise tools for method development and impurity profiling.

Application

• Pre-column derivatization agent for the HPLC and LC-MS analysis of primary and secondary amines.
• Fluorescent labeling reagent in proteomics and metabolomics for detecting low-abundance biomolecules.
• Bioconjugation tool for tagging proteins, peptides, and antibodies in diagnostic assay development.
• Quality control testing in pharmaceutical manufacturing for the analysis of drug substances and related impurities.
• Research chemical in academic and industrial settings for studying enzyme kinetics and reaction mechanisms.
• Derivatization for capillary electrophoresis (CE) to improve the detection limits of analytes.

Basic Information

Product Name	Dansyl Ethylenediamine Hydrochloride
CAS No.	1092458-66-6
Molecular Formula	C14H19N3O2S • HCl
Molecular Weight	329.84 g/mol (Free base: 293.38)
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonyl ethylenediamine hydrochloride; Dansyl-EDA HCl; DNS-EDA hydrochloride; 1-Dimethylaminonaphthalene-5-sulfonylethylenediamine HCl; N1-(5-Dimethylaminonaphthalene-1-sulfonyl)ethane-1,2-diamine hydrochloride; DENSYL ETHYLENEDIAMINE HYDROCHLORIDE; Fluorescent derivatization reagent
EINECS	Contact for details

Quality Control

Our Dansyl Ethylenediamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.