Description

6-Benzyl-3,5,6,7-Tetrahydropyrrolo[3,4-D]Pyrimidin-4-One is a high-purity heterocyclic organic compound with the CAS number 1092352-66-3, serving as a critical pharmaceutical intermediate and research chemical. Its unique pyrrolopyrimidinone scaffold makes it a valuable building block for medicinal chemistry, particularly in the development of kinase inhibitors and other bioactive molecules. This product is essential for R&D laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Kinase Inhibitor Research: Serves as a core scaffold for designing and synthesizing potent and selective kinase inhibitors due to its privileged structure.
• Medicinal Chemistry & Drug Discovery: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Biochemical Research: Employed as a tool compound or reference standard in enzymatic assays and biological screening.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Benzyl-3,5,6,7-Tetrahydropyrrolo[3,4-D]Pyrimidin-4-One
CAS No.	1092352-66-3
Molecular Formula	C₁₅H₁₅N₃O
Molecular Weight	253.30 g/mol
Synonyms	6-Benzyl-3,5,6,7-tetrahydropyrrolo[3,4-d]pyrimidin-4(3H)-one; 6-Benzyl-4-oxo-3,4,5,6,7,8-hexahydropyrrolo[3,4-d]pyrimidine; 6-Benzyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidin-4(3H)-one; 1092352-66-3; Pyrrolo[3,4-d]pyrimidin-4-one, 6-benzyl-3,5,6,7-tetrahydro-
EINECS	Contact for details

Quality Control

Every batch of 6-Benzyl-3,5,6,7-Tetrahydropyrrolo[3,4-D]Pyrimidin-4-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for each lot. Our quality commitment supports compliance with relevant guidelines for research use and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.