Description

2-Chloro-4-Quinazolinecarboxylic Acid Ethyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of quinazoline-based compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic molecules for agrochemical and material science applications.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-Chloro-4-Quinazolinecarboxylic Acid Ethyl Ester
CAS No.	1092352-52-7
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.65 g/mol
Synonyms	Ethyl 2-Chloro-4-quinazolinecarboxylate; 2-Chloroquinazoline-4-carboxylic Acid Ethyl Ester; 4-Quinazolinecarboxylic Acid, 2-Chloro-, Ethyl Ester; Ethyl 2-Chloro-4-quinazolinecarboxylate; 2-Chloro-4-(ethoxycarbonyl)quinazoline; 2-Chloro-4-carbethoxyquinazoline; Quinazoline-4-carboxylic Acid, 2-Chloro-, Ethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Quinazolinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.