Description

7-(Trifluoromethyl)Quinoline-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block characterized by its quinoline core and trifluoromethyl substituent. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and bioactivity.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for catalysis, and fluorescent dyes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Coordination Chemistry: Acts as a chelating ligand for metal complexes used in catalysis and imaging applications.

Basic Information

Product Name	7-(Trifluoromethyl)Quinoline-2-Carboxylic Acid
CAS No.	1092304-95-4
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	2-Quinolinecarboxylic acid, 7-(trifluoromethyl)-; 7-(Trifluoromethyl)-2-quinolinecarboxylic acid; 7-Trifluoromethylquinoline-2-carboxylic acid; 7-CF3-Quinoline-2-carboxylic acid; 7-(Trifluoromethyl)quinoline-2-carboxylate; 1092304-95-4; 7-(Trifluoromethyl)-2-carboxyquinoline
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Quinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting standards for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.