Description

8-(Trifluoromethyl)Quinolin-2-Amine is a high-value, fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a reactive amine group and a stable trifluoromethyl moiety, makes it indispensable for creating compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targets in oncology, central nervous system (CNS) disorders, and anti-infective therapies.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging reagent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Fluorine Chemistry: A valuable substrate for further fluorination reactions and the study of structure-activity relationships (SAR) influenced by the CF3 group.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	8-(Trifluoromethyl)Quinolin-2-Amine
CAS No.	1092304-80-7
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	2-Amino-8-(trifluoromethyl)quinoline; 8-Trifluoromethylquinolin-2-amine; 2-Quinolinamine, 8-(trifluoromethyl)-; Quinolin-2-amine, 8-(trifluoromethyl)-; 8-CF3-Quinolin-2-ylamine; 8-Trifluoromethyl-2-aminoquinoline; 2-Amino-8-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Every batch of 8-(Trifluoromethyl)Quinolin-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.