Description

2-Chloroquinoline-8-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a chlorinated quinoline core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for kinase inhibitors, antimicrobials, and anti-inflammatory agents.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand Synthesis: Used to prepare complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the creation of organic semiconductors, fluorescent dyes, and advanced polymers.
• Chemical Biology: Utilized as a probe or linker molecule in bioconjugation and the study of biological pathways.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Chloroquinoline-8-Carboxylic Acid
CAS No.	1092287-54-1
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	8-Quinolinecarboxylic acid, 2-chloro-; 2-Chloro-8-quinolinecarboxylic acid; 2-Chloroquinoline-8-carboxylic acid; 2-Chloro-8-quinoline carboxylic acid; 2-Chloro-8-carboxyquinoline; 2-Cl-8-QuinCOOH; 1092287-54-1; 2-Chloro-8-quinolylcarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloroquinoline-8-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical research and development processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment, confirming compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.