Description

3-Hydroxy-Cyclobutanecarboxylic Acid Methylamide is a versatile and synthetically valuable cyclobutane derivative, serving as a crucial chiral building block in advanced organic synthesis. Its unique fused ring structure with both hydroxy and amide functionalities makes it an essential intermediate for constructing complex molecular architectures with high stereochemical control. This compound is particularly sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific three-dimensional structural motifs.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or building block for specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, particularly in ring-opening and functionalization reactions.

Basic Information

Product Name	3-Hydroxy-Cyclobutanecarboxylic Acid Methylamide
CAS No.	1089340-69-1
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	3-Hydroxycyclobutanecarboxymethylamide; Methylamide of 3-hydroxycyclobutanecarboxylic acid; 3-Hydroxycyclobutanecarboxylic acid methyl amide; N-Methyl-3-hydroxycyclobutanecarboxamide; (3-Hydroxycyclobutyl)(methyl)carbamic acid (tautomeric form); 1089340-69-1; 3-Hydroxy-N-methylcyclobutanecarboxamide
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-Cyclobutanecarboxylic Acid Methylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.