Description

S-2-Quinolinealanine Hihydrochloride is a high-purity, non-proteinogenic amino acid derivative featuring a quinoline moiety, primarily utilized as a critical building block in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel peptide-based therapeutics and as a chiral intermediate in medicinal chemistry. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focused on developing targeted drug candidates and molecular probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in oncology and neurology research.
• Peptide Synthesis: Used as a specialized, non-natural amino acid residue in solid-phase and solution-phase peptide synthesis to modulate biological activity and stability.
• Medicinal Chemistry Research: Serves as a crucial building block for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Bioconjugation: Acts as a linker or functional handle for labeling peptides and proteins in biochemical assay development.
• Academic & Institutional R&D: Employed in university and research institute laboratories for fundamental studies in chemical biology and organic synthesis.
• Reference Standard: Suitable for use as an analytical standard in quality control and method development for related pharmaceutical compounds.

Basic Information

Product Name	S-2-Quinolinealanine Hihydrochloride
CAS No.	1087751-63-0
Molecular Formula	C₁₂H₁₃Cl₂N₃O₂
Molecular Weight	302.15 g/mol
Synonyms	(S)-2-Amino-3-(quinolin-2-yl)propanoic acid dihydrochloride; L-2-Quinolinealanine dihydrochloride; (S)-2-Quinolin-2-ylalanine dihydrochloride; 2-Quinolinyl-L-alanine dihydrochloride; Quinoline-2-yl-L-alanine 2HCl; S-2-Qal(2HCl); L-(2-Quinolyl)alanine hydrochloride
EINECS	Contact for details

Quality Control

Our S-2-Quinolinealanine Hihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.