Description

2,5-Diazaspiro[3.4]Octane-5-Carboxylicacid-1,1-Dimethylethylester is a high-value, spirocyclic building block featuring a unique bicyclic scaffold that incorporates both nitrogen heteroatoms and a carboxylic acid ester functional group. This compound is critical for medicinal chemistry research and development, enabling the rapid synthesis of novel, three-dimensional molecular architectures. It is primarily utilized by pharmaceutical and biotechnology companies as a key intermediate in the design and synthesis of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A versatile scaffold for constructing novel drug candidates, especially in CNS and oncology therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization programs to explore new chemical space and improve drug-like properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional degraders.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for target validation and pathway analysis.
• Agrochemical Research: Investigated as a building block for novel crop protection agents due to its complex, spirocyclic structure.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	2,5-Diazaspiro[3.4]Octane-5-Carboxylicacid-1,1-Dimethylethylester
CAS No.	1086398-04-0
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl 2,5-diazaspiro[3.4]octane-5-carboxylate; 2,5-Diazaspiro[3.4]octane-5-carboxylic acid tert-butyl ester; 5-(tert-Butoxycarbonyl)-2,5-diazaspiro[3.4]octane; 2,5-Diazaspiro[3.4]octane-5-carboxylic acid 1,1-dimethylethyl ester; Boc-2,5-diazaspiro[3.4]octane; 2,5-Diazaspiro[3.4]octane, 5-Boc-protected; Spirocyclic diaza building block
EINECS	Contact for details

Quality Control

Our 2,5-Diazaspiro[3.4]Octane-5-Carboxylicacid-1,1-Dimethylethylester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided for traceability and to support your regulatory filings. We can supply material compliant with research, development, and cGMP standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.