Description

2,5-Diazaspiro[3.4]Octane-2-Carboxylic Acid, 1,1-Dimethylethyl Ester is a high-value, protected spirocyclic amino acid derivative that serves as a critical building block in modern organic synthesis. Its rigid, three-dimensional spirocyclic structure is essential for constructing complex molecular architectures with enhanced biological activity and selectivity. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including protease inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for targeting central nervous system (CNS) disorders and infectious diseases.
• Protease Inhibitor Scaffold: Used to construct the core framework of potent inhibitors for various enzymes like proteases and kinases.
• Agrochemical Synthesis: Employed in creating advanced, bioactive molecules for crop protection products with novel modes of action.
• Peptidomimetics & Constrained Peptides: Integral for designing and synthesizing peptide analogs with improved metabolic stability and bioavailability.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold in fragment-based drug discovery and structure-activity relationship (SAR) studies.
• Advanced Material Research: Potential precursor for specialty polymers and ligands used in catalysis and material science.

Basic Information

Product Name	2,5-Diazaspiro[3.4]Octane-2-Carboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	1086398-02-8
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	tert-Butyl 2,5-diazaspiro[3.4]octane-2-carboxylate; 1,1-Dimethylethyl 2,5-Diazaspiro[3.4]octane-2-carboxylate; Boc-2,5-Diazaspiro[3.4]octane; 2-(tert-Butoxycarbonyl)-2,5-diazaspiro[3.4]octane; 2,5-Diazaspiro[3.4]octane-2-carboxylic acid tert-butyl ester; N-Boc-2,5-diazaspiro[3.4]octane; Spirocyclic Amino Acid Ester; 1086398-02-8
EINECS	Contact for details

Quality Control

Our production of 2,5-Diazaspiro[3.4]Octane-2-Carboxylic Acid, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards of pharmaceutical R&D. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.