Description

2,6-Diazaspiro[4.5]Decane, 2-(Phenylmethyl)- is a high-value, nitrogen-containing spirocyclic building block with significant utility in advanced organic synthesis. Its unique constrained bicyclic structure, featuring a spiro center and a benzyl-protected secondary amine, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst ligand design.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in programs targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Scaffold: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its three-dimensional, shape-defined spirocyclic core.
• Ligand Synthesis: Serves as a precursor for the development of novel chiral and achiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the discovery and development of new herbicides, fungicides, and insecticides that require sophisticated nitrogen heterocycles.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Academic Research: A valuable reagent for methodological studies in organic synthesis, particularly in spirocycle formation and amine functionalization chemistry.

Basic Information

Product Name	2,6-Diazaspiro[4.5]Decane, 2-(Phenylmethyl)-
CAS No.	1086395-73-4
Molecular Formula	C15H22N2
Molecular Weight	230.35 g/mol
Synonyms	2-Benzyl-2,6-diazaspiro[4.5]decane; 2-Benzyl-2,6-diaza-spiro[4.5]decane; 2-(Phenylmethyl)-2,6-diazaspiro[4.5]decane; 2,6-Diazaspiro[4.5]decane, 2-benzyl-; 1086395-73-4; 2-Benzyl-2,6-diazaspiro[4.5]decane; N-Benzyl-2,6-diazaspiro[4.5]decane; Spiro[4.5]decane, 2-benzyl-2,6-diaza-
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[4.5]Decane, 2-(Phenylmethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications including assay (by HPLC), related substances, residual solvents, and other critical parameters. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to minimize exposure to moisture and oxygen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.