Description

7-(Trifluoromethyl)-3,4-Dihydro-2H-1,4-Benzoxazine-2-Carboxylicacid is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a benzoxazine ring and a carboxylic acid group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Acts as a monomer or functionalizing agent for developing specialty polymers and advanced materials with unique surface properties.
• Ligand and Catalyst Development: Employed in the synthesis of complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the introduction of fluorine atoms into complex molecular architectures.

Basic Information

Product Name	7-(Trifluoromethyl)-3,4-Dihydro-2H-1,4-Benzoxazine-2-Carboxylicacid
CAS No.	1086380-46-2
Molecular Formula	C10H8F3NO3
Molecular Weight	247.17 g/mol
Synonyms	7-(Trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid; 2H-1,4-Benzoxazine-2-carboxylic acid, 3,4-dihydro-7-(trifluoromethyl)-; 1086380-46-2; 7-Trifluoromethyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid; 7-(Trifluoromethyl)-2H-1,4-benzoxazine-2-carboxylic acid, 3,4-dihydro-
EINECS	Contact for details

Quality Control

Our production of 7-(Trifluoromethyl)-3,4-Dihydro-2H-1,4-Benzoxazine-2-Carboxylicacid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. All materials are fully characterized using advanced analytical techniques, including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.