Description

7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydroquinoline-3-Carboxylicacid is a high-purity, advanced pharmaceutical intermediate characterized by its specific tetrahydroquinoline core structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile scaffold for medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as oncology and neurology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with tetrahydroquinoline-based pharmacophores.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds for academic and industrial research.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydroquinoline-3-Carboxylicacid
CAS No.	1086375-47-4
Molecular Formula	C₁₂H₁₃NO₃
Molecular Weight	219.24 g/mol
Synonyms	7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 5,6,7,8-tetrahydro-7,7-dimethyl-5-oxo-; 7,7-Dimethyl-5-oxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carboxylic acid; 5-Oxo-7,7-dimethyl-5,6,7,8-tetrahydroquinoline-3-carboxylic acid; Tetrahydroquinoline-3-carboxylic acid derivative; CAS 1086375-47-4
EINECS	Contact for details

Quality Control

Our 7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydroquinoline-3-Carboxylicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.