Description

1'-Benzylspiro[Indoline-3,4'-Piperidin]-2-One is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic molecular architecture. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those with spirocyclic or fused heterocyclic structures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to develop new chemical entities with improved efficacy and safety profiles.
• CNS Drug Discovery: Serves as a core scaffold for developing compounds targeting neurological receptors and enzymes, applicable in research for neurodegenerative diseases, psychiatric disorders, and pain management.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Custom Synthesis Building Block: Employed by fine chemical suppliers for the contract manufacturing of specialized, high-value compounds for client R&D projects.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and pharmacology studies.

Basic Information

Item	Detail
Product Name	1'-Benzylspiro[Indoline-3,4'-Piperidin]-2-One
CAS No.	1086063-19-5
Molecular Formula	C20H20N2O
Molecular Weight	304.39 g/mol
Synonyms	1'-Benzylspiro[indoline-3,4'-piperidin]-2-one; Spiro[indoline-3,4'-piperidine]-2-one, 1'-benzyl-; 1'-Benzyl-1'H-spiro[indoline-3,4'-piperidin]-2-one; 1'-Benzylspiro[indole-3,4'-piperidine]-2(1H)-one; 1086063-19-5; Benzylspiroindolinone piperidine derivative
EINECS	Contact for details

Quality Control

Our 1'-Benzylspiro[Indoline-3,4'-Piperidin]-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with standards expected for pharmaceutical intermediates in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.