Description

5-(3-Fluorophenyl)-1,3-Oxazole-4-Carboxylic Acid is a high-value fluorinated oxazole derivative, a key heterocyclic building block in advanced organic synthesis. This compound is prized for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique fluorinated aromatic-oxazole scaffold.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorophenyl-oxazole moiety can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, organic semiconductors, and fluorinated polymers with tailored electronic properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and scale-up development.

Basic Information

Product Name	5-(3-Fluorophenyl)-1,3-Oxazole-4-Carboxylic Acid
CAS No.	1083401-22-2
Molecular Formula	C10H6FNO3
Molecular Weight	207.16 g/mol
Synonyms	5-(3-Fluorophenyl)-4-oxazolecarboxylic acid; 4-Oxazolecarboxylic acid, 5-(3-fluorophenyl)-; 5-(3-Fluorophenyl)oxazole-4-carboxylic acid; 3-Fluoro-5-(4-carboxyoxazol-5-yl)benzene; 1083401-22-2; 5-(m-Fluorophenyl)-1,3-oxazole-4-carboxylic acid; 5-(3-Fluorophenyl)-1,3-oxazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(3-Fluorophenyl)-1,3-Oxazole-4-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.