Description

5-(4-Fluorophenyl)-1,3-Oxazole-4-Carboxylic Acid is a high-purity fluorinated oxazole derivative, a critical building block in modern synthetic organic chemistry. This compound is valued for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated oxazole core.
• Material Science Precursor: Serves as a monomer or functional additive in the research of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	5-(4-Fluorophenyl)-1,3-Oxazole-4-Carboxylic Acid
CAS No.	1083246-33-6
Molecular Formula	C10H6FNO3
Molecular Weight	207.16 g/mol
Synonyms	4-Fluoro-α,β-didehydro-α-oxo-1H-5-oxazolebutanoic acid; 5-(4-Fluorophenyl)-4-oxazolecarboxylic acid; 5-(p-Fluorophenyl)oxazole-4-carboxylic acid; 4-Carboxy-5-(4-fluorophenyl)oxazole; 1083246-33-6; 5-(4-Fluorophenyl)-1,3-oxazole-4-carboxylic acid; 5-(4-Fluorophenyl)oxazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)-1,3-Oxazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.