Description

4-(Trifluoromethoxy)Indan-1-Amine Hcl is a high-purity, advanced pharmaceutical intermediate characterized by its indane backbone and trifluoromethoxy substituent. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific fluorine chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorinated Compound Production: Employed in the synthesis of various fluorinated fine chemicals and specialty materials.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-(Trifluoromethoxy)Indan-1-Amine Hcl
CAS No.	1083090-92-9
Molecular Formula	C10H11F3NO•HCl
Molecular Weight	253.66 g/mol
Synonyms	1-Amino-4-(trifluoromethoxy)indane hydrochloride; 4-(Trifluoromethoxy)-1-indanamine hydrochloride; 4-(Trifluoromethoxy)indan-1-amine hydrochloride; 1-Indanamine, 4-(trifluoromethoxy)-, hydrochloride; 4-TFMO-Indan-1-Amine HCl; 1083090-92-9
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Indan-1-Amine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.