Description

(S)-2-Amino-3-(Pyridin-2-Yl)Propanoic Acid Dihydrochloride is a high-purity, non-natural amino acid derivative, specifically the dihydrochloride salt of the (S)-enantiomer. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a pyridylalanine moiety, influencing peptide conformation and receptor binding.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for chiral separation.
• Ligand Synthesis: Serves as a precursor for creating chiral ligands used in asymmetric catalysis and metal complexation.
• Prodrug Development: Utilized in the design and synthesis of prodrugs to enhance bioavailability and targeting.
• Chemical Biology Probes: Incorporated into molecular probes for studying protein-protein interactions and cellular signaling pathways.

Basic Information

Item	Detail
Product Name	(S)-2-Amino-3-(Pyridin-2-Yl)Propanoic Acid Dihydrochloride
CAS No.	1082692-96-3
Molecular Formula	C8H12Cl2N2O2
Molecular Weight	239.10 g/mol
Synonyms	(S)-2-Amino-3-(2-Pyridyl)propanoic Acid Dihydrochloride; (S)-2-Pyridylalanine Dihydrochloride; (S)-β-(2-Pyridyl)-L-alanine Dihydrochloride; L-2-Pyridylalanine Dihydrochloride; (S)-3-(Pyridin-2-yl)-L-alanine Dihydrochloride; (2S)-2-Amino-3-(pyridin-2-yl)propanoic Acid Dihydrochloride; (S)-2-Amino-3-(2-Pyridinyl)propanoic Acid Hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-(Pyridin-2-Yl)Propanoic Acid Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.