Description

trans-Cyclohexane-1,3-Diamine Hydrochloride is a high-purity, stereochemically defined diamine salt used as a critical chiral building block and ligand precursor in advanced organic synthesis. Its rigid trans-cyclohexane backbone provides unique steric and electronic properties, enabling precise control over reaction pathways and product stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective hydrogenation, alkylation, and other C-C bond-forming reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Polymer Modification: Acts as a curing agent, cross-linker, or monomer for producing high-performance polyamides, polyurethanes, and epoxy resins with improved thermal and mechanical properties.
• Chelating Agent: Forms stable complexes with metal ions for applications in catalysis, metal extraction, and wastewater treatment.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and material science.

Basic Information

Product Name	trans-Cyclohexane-1,3-Diamine Hydrochloride
CAS No.	1082681-41-1
Molecular Formula	C6H14N2·HCl
Molecular Weight	150.65 g/mol
Synonyms	(1R,3S)-1,3-Cyclohexanediamine Hydrochloride; (1S,3R)-1,3-Cyclohexanediamine Hydrochloride; trans-1,3-Diaminocyclohexane Hydrochloride; trans-1,3-CHDA·HCl; (1R,3S)-Cyclohexane-1,3-diamine Hydrochloride; (1S,3R)-Cyclohexane-1,3-diamine Hydrochloride; 1,3-DACH·HCl (trans); trans-1,3-Bis(aminomethyl)cyclohexane Hydrochloride
EINECS	Contact for details

Quality Control

Our trans-Cyclohexane-1,3-Diamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.