Description

1H-Pyrrolo[3,2-C]Pyridine, 7-Bromo-4-Fluoro- is a high-value, multi-functional heterocyclic building block, essential for advanced synthetic chemistry. Its core value lies in its unique fused bicyclic structure, which incorporates both bromo and fluoro substituents, enabling precise molecular modifications and serving as a key intermediate in the development of complex active compounds. This compound is critically needed by pharmaceutical and agrochemical research organizations for applications in drug discovery, medicinal chemistry, and the synthesis of novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile reactivity profile.
• Agrochemical Synthesis: Serves as a key precursor in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Potential application in the synthesis of organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex molecular architectures.
• Fluorination Chemistry: The presence of the fluorine atom allows for further derivatization, exploiting the unique properties fluorine imparts to molecules, such as metabolic stability and membrane permeability.

Basic Information

Item	Detail
Product Name	1H-Pyrrolo[3,2-C]Pyridine, 7-Bromo-4-Fluoro-
CAS No.	1082041-10-8
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	7-Bromo-4-fluoro-1H-pyrrolo[3,2-c]pyridine; 4-Fluoro-7-bromo-1H-pyrrolo[3,2-c]pyridine; 7-Bromo-4-fluoro-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 7-bromo-4-fluoro-; 1082041-10-8; 7-Br-4-F-1H-pyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-C]Pyridine, 7-Bromo-4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.