Description

8-Bromoquinoline, Hcl is a halogenated quinoline derivative, a versatile and high-value organic building block crucial for advanced chemical synthesis. Its primary value lies in its role as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is particularly sought after by R&D chemists and process development scientists working in medicinal chemistry, material science, and fine chemical manufacturing. The bromine atom at the 8-position offers a reactive handle for further functionalization via cross-coupling reactions, enabling the creation of novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with quinoline-based pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for creating organic ligands in catalysis and for synthesizing advanced organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form carbon-carbon and carbon-heteroatom bonds.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways.
• Fine Chemical Synthesis: Employed in custom and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	8-Bromoquinoline, Hcl
CAS No.	1081803-09-9
Molecular Formula	C9H7BrN • HCl
Molecular Weight	260.52 g/mol
Synonyms	8-Bromoquinoline hydrochloride; Quinoline, 8-bromo-, hydrochloride; 8-Bromoquinoline HCl salt; 8-Bromo-quinoline hydrochloride; 8-BQ•HCl
EINECS	Contact for details

Quality Control

Every batch of 8-Bromoquinoline, Hcl is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.