Description

2-Fluoro-3-Iodoanisole is a high-purity fluorinated and iodinated aromatic ether building block. This compound is valued for its dual halogen functionality, which provides distinct reactivity for selective cross-coupling and substitution reactions in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a versatile precursor for creating new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Material Research: Used in the synthesis of fluorinated and iodinated organic semiconductors and liquid crystal molecules for electronic displays and lighting.
• Cross-Coupling Reactions: The iodine moiety is highly reactive in palladium-catalyzed reactions (e.g., Suzuki, Stille, Sonogashira), while the fluorine can influence electronic properties and metabolic stability.
• Chemical Biology & Radiolabeling Probes: The iodine atom allows for potential radioiodination (123I, 125I) for imaging and diagnostic applications, or as a stable label in tracer studies.
• Material Science Building Block: Employed in the synthesis of specialized polymers, ligands for catalysis, and advanced organic frameworks.

Basic Information

Product Name	2-Fluoro-3-Iodoanisole
CAS No.	1080673-30-8
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	1-Fluoro-2-Iodo-3-Methoxybenzene; 3-Iodo-2-Fluoroanisole; 2-Fluoro-3-Iodomethoxybenzene; 2-Fluoro-3-Iodophenyl Methyl Ether; 1-Methoxy-2-fluoro-3-iodobenzene; Benzene, 1-fluoro-2-iodo-3-methoxy-; 3-Methoxy-2-fluoro-1-iodobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodoanisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Purity (HPLC/GC)	≥99.0% (High Purity Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.